
Is Ayahuasca Safe?
Learn exactly how we screen, prepare, and protect every participant - and whether ayahuasca is right for you.
Takes 2 minutes. Private. No commitment.
Safety First
Is Ayahuasca Safe?
Ayahuasca can be safe when conducted in a properly screened, medically aware, and professionally facilitated environment.
Safety is conditional
However, without these safeguards, it carries real psychological and physiological risks.
The question is not only whether ayahuasca is safe in general, but whether it is safe for your body, your mental health, your medications, and the setting you choose.
The experience is intense
Ayahuasca can bring intense physical effects such as nausea, purging, changes in body temperature, and temporary increases in heart rate or blood pressure.
Psychologically, it can open vivid imagery, deep emotional release, fear, grief, insight, and memories that require steady support.
You are not just taking a substance. You are entering a powerful inner process.
The container matters
Safety varies widely across the global retreat landscape, including Peru, Costa Rica, Colombia, and underground settings elsewhere.
The country matters less than the actual container: honest medical screening, experienced facilitation, clear emergency judgment, appropriate group size, and integration support.
A strong container is what turns risk into a transformative experience.
In short
In the right hands, ayahuasca can be profoundly healing. Our medical screening exists to make sure those hands are the right fit for you - before you ever arrive.
Your safety is the foundation of your journey.
Our Safety Approach
Four pillars that ensure your wellbeing throughout the journey
Medical Screening
Every participant completes a comprehensive health questionnaire. We review your medical history, current medications, and mental health background to ensure ayahuasca is appropriate for you.
Experienced Guidance
Our ceremonies are led by taitas with 15+ years of experience, supported by trained facilitators who remain present throughout to ensure physical and emotional safety.
Careful Preparation
We provide detailed preparation guidelines including dietary restrictions, medication protocols, and intention-setting practices to optimize your safety and experience.
Ongoing Support
Your safety extends beyond the ceremony. We offer integration support and remain available for questions and concerns before, during, and after your retreat.
Check if you may be eligible
Answer three quick questions about medications, mental health history, and physical health. This does not replace medical screening, but it can help you understand your next step.
Who Should Not Take Ayahuasca (Contraindications & Risks)
Certain conditions and medications are contraindicated with ayahuasca. This is not a complete list-we review each application individually.
- Heart conditions (particularly serious cardiac issues)
- Uncontrolled high blood pressure
- History of psychosis, schizophrenia, or severe mental illness
- Bipolar disorder (particularly during manic episodes)
- Currently taking MAOIs, SSRIs, or SNRIs
- Taking blood pressure medications
- Pregnancy or breastfeeding
- Recent surgery or serious physical conditions
- Active substance addiction (especially stimulants)
If you have any of these conditions or are taking related medications, please be honest in your application. We may still be able to work with you, or we can recommend alternative approaches.
Is Ayahuasca Dangerous for Mental Health?
Ayahuasca can intensify underlying psychological conditions.
It is not recommended for individuals with:
- History of psychosis or schizophrenia
- Severe bipolar disorder
- Unstable mental health conditions
These conditions can worsen significantly during the experience.
Can You Take Ayahuasca While on Antidepressants?
In general, no.
Ayahuasca contains MAOIs, which interact dangerously with:
- SSRIs
- SNRIs
- Other antidepressants
This can lead to serotonin syndrome, a potentially life-threatening condition.
Is Ayahuasca Safe for People with Heart Conditions?
Ayahuasca increases heart rate and blood pressure.
It is unsafe for individuals with:
- Cardiovascular disease
- Uncontrolled hypertension
Medical screening is essential before participation.
If you are unsure whether ayahuasca is safe for you, do not guess. Contact us so we can talk with you directly. Proper screening is essential.
Medical Review
Our Screening Process
Safety begins before anyone enters ceremony. We review health history, medications, mental health background, and risk factors so ayahuasca is approached with clear limits rather than guesswork.

Medical Advisor
Dr. Marta Turpin
Medical Advisor
Dr. Marta Turpin
Dr. Marta Turpin supports Camino al Sol as medical advisor, helping guide our health intake standards, risk awareness, and screening protocols.
Her role strengthens the bridge between traditional ceremony and responsible medical caution, especially around medications, cardiovascular concerns, and contraindications.
Initial Application
You complete our detailed health questionnaire covering medical history, current medications, mental health, and lifestyle factors.
Team Review
Our team-including facilitators with medical backgrounds-reviews your application to identify any concerns.
Personal Discussion
If we have questions or concerns, we schedule a call to discuss your situation in depth and answer your questions.
Clear Decision
We provide a clear decision. If accepted, you receive detailed preparation guidelines. If not, we explain why and may suggest alternatives.
Preparation Guidelines
Proper preparation enhances safety and deepens your experience
The Dieta (Dietary Preparation)
- Avoid processed foods for 5-7 days before ceremony
- Eliminate alcohol for at least 3-5 days before
- Stop recreational drugs at least 2 weeks before
- Follow specific medication tapering guidelines (provided individually)
- Reduce caffeine intake
- Avoid sexual activity for 3 days before ceremony
Mental & Spiritual Preparation
- Set clear intentions for your journey
- Practice meditation or quiet reflection
Detailed preparation instructions are provided after acceptance to your specific retreat.
How Long Does Ayahuasca Last
- Active effects: 4–8 hours
- Peak intensity: 1–3 hours
- After-effects: up to 24 hours
- Integration: days to weeks
This is a long, intense experience that requires proper preparation and support.
Integration: After the Ceremony
The work continues after you leave the ceremony space
Integration is the process of making sense of your experience and applying insights to your daily life. It's a crucial part of safe and effective work with plant medicine.
- Take time to rest and reflect after returning home
- Journal about your experience while memories are fresh
- Maintain the clean diet for several days after
- Seek support from understanding friends or a therapist
- Be patient-insights often unfold over weeks or months
- Consider a follow-up integration session with our team
Integration Support
We offer optional integration sessions in the weeks following your retreat. These can be helpful for processing complex experiences and ensuring lasting benefit from your journey.
Further reading: Integration & SupportFrequently Asked Questions
Have Questions About Safety?
We're happy to answer any questions about our safety protocols, the screening process, or whether ayahuasca is right for you.